JenKem Technology USA  published recently an invited review in Modern Chemistry and Applications, in collaboration with Clarkson University, focused on applications of PEGs and PEG derivatives in drug development, medical device, diagnostics, and regenerative medicine. These applications were reported by the scientific community in 2014. To learn more about applications of JenKem Technology PEGs, please also visit our website.

Applications JenKem PEGs

Featured JenKem PEG products are included in the table below (Reproduced with permission from: Hutanu D, Frishberg MD, Guo L, Darie CC (2014) Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem appl 2:132. doi: 10.4172/2329-6798.1000132):

Polyethylene Glycol (PEG) Compound PEG Applications Reference
Biotin PEG SGA Ester, MW 3500 Cell PEGylation [26]
Methoxy PEG Amine, HCl Salt, MW 2000 Diagnostics [57]
4arm PEG Succinimidyl Carboxymethyl Ester, MW 40000 Drug delivery [24]
Maleimide PEG Amine, MW 3500 Drug delivery [2]
Maleimide PEG Hydroxyl, MW 3500 Drug delivery [58]
Maleimide PEG NHS Ester MW 1000 Drug delivery [59]
Maleimide PEG NHS Ester, MW 2000 Drug delivery [21]
Maleimide PEG NHS Ester, MW 3500 Drug delivery [59]
Maleimide PEG NHS Ester, MW 5000 Drug delivery [60]
Methoxy PEG Amine, MW 12kDa Drug delivery [61]
Methoxy PEG Amine, MW 20kDa Drug delivery [62]
Methoxy PEG Carboxyl, MW 3500 Drug delivery [32]
Methoxy PEG Carboxyl, MW 1000 Drug delivery [63]
Methoxy PEG NHS Ester, MW 5000 Drug delivery [60]
Methoxy PEG Propionaldehyde, MW 5000, MW 20kDa Drug delivery [62]
PEG Maleimide, MW 10000 Drug delivery [22]
PEG NHS Ester MW 5000 Drug delivery [59]
PEG Succinimidyl Carbonate, MW 10000 Drug delivery [22]
PEG Thiol, MW 5000 Drug delivery [59]
Amine PEG Carboxyl, HCl Salt, MW 5000 Drug delivery, Diagnostics [3]
t-Boc Amine PEG Amine, HCl Salt, MW 5000 Drug delivery, Diagnostics [3]
Amine PEG Carboxyl MW 3500 Drug delivery, Nanoparticle PEGylation [64]
Methoxy PEG Amine MW 3500 Drug delivery, Nanoparticle PEGylation [64]
4arm PEG Succinimidyl Carboxymethyl Ester, MW 10000 Hydrogel [55]
4arm PEG Amine, MW 20kDa Hydrogel [14], [50]¸ [53]
4arm PEG Thiol MW 10kDa Hydrogel [41]
4arm Polyethylene Glycol MW 10kDa Hydrogel [41]
4arm Polyethylene Glycol MW 20kDa Hydrogel [14],[43],[40],[45],[46],[50]
4arm Polyethylene Glycol MW 40kDa Hydrogel [46]
4arm Polyethylene Glycol, MW 5000 Hydrogel [56]
8arm PEG Amine (tripentaerythritol), HCl Salt, MW 40000 Hydrogel [39]
8arm PEG Amine HCl Salt MW 10kDa Hydrogel [47]
8arm PEG Thiol (hexaglycerol), MW 10000 Hydrogel [44]
8arm Polyethylene Glycol (hexaglycerol), MW 10000 Hydrogel [44],[53]
8arm Polyethylene Glycol (hexaglycerol), MW 15000 Hydrogel [49]
8arm Polyethylene Glycol (hexaglycerol), MW 20000, MW 40000 Hydrogel [38]
Acrylate PEG NHS Ester MW 3500 Hydrogel [42], [48]
Methoxy PEG Amine, MW 2000 Hydrogel [54]
6arm PEG Amine MW 10kDa Nanoparticle PEGylation [29]
Methoxy PEG Amine, MW 10000 Nanoparticle PEGylation [65]
MPEG Amine, MW 2000 Nanoparticle PEGylation [29]
PEG NHS Ester MW 10kDa, MW 20kDa, MW 40kDa Nanoparticle PEGylation [27]
Thiol PEG Amine, MW 5000 Nanoparticle PEGylation [28]
Methoxy PEG Amine, MW 5000 Nanoparticle PEGylation, Drug delivery [30],[62]
Methoxy Polyethylene Glycol, MW 5000 Nanoparticle PEGylation, Drug delivery [30]
8arm Polyethylene Glycol (tripentaerythritol), MW 20000 Peptide PEGylation [19]
Methoxy PEG Amine HCl Salt MW 5000 Peptide PEGylation [20]
Biotin PEG NHS Ester Peptide PEGylation [35]
Methoxy PEG NHS Ester Peptide PEGylation [35]
Thiol PEG Carboxyl, MW 5000 Protein and Nanoparticle PEGylation [23]
PEG Amine, HCl Salt, MW 20000 Surface modification [33]
PLL20k-G35-PEG2k Surface modification [34],[36],[37]”