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Homobifunctional PEGs

JenKem Technology homobifunctional PEG derivatives have numerous applications as cross-linkers, including for PEGylation of proteins and peptides, or nanoparticle and surface modifications. Homobifunctional PEG derivatives have the general structure: X―PEG―X, where X is a functional or reactive group.

JenKem homobifunctional PEG products with molecular weights and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at tech@jenkemusa.com about pricing and availability of custom homofunctional PEGs.

JenKem Technology provides GMP grade PEG derivatives and bulk orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. JenKem Technology is capable of development and synthesis of a wide range of GMP PEG derivatives starting at 200g up to 40 kg or greater batches, under ISO 9001 and ISO 13485 certified quality management system, following ICH Q7A guidelines. For inquiries on cGMP production of PEG derivatives please contact us at tech@jenkemusa.com.

Amine PEGylation Homobifunctional PEGs

Homobifunctional PEGs for Carboxyl PEGylation

Homobifunctional PEGs for Thiol PEGylation

Homobifunctional PEGs for Click Chemistry

Photoreactive Homobifunctional PEGs

3ARM, 4ARM, 6ARM, and 8ARM Homofunctional PEGs


Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.

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