Product categories

PEG Products

AboutJenKemPEGSynthesisJenKem Technology manufactures high quality activated PEG polymers, PEG co-polymers, and monodisperse PEGs, from laboratory to commercial scale. Our reactive polyethylene glycol derivatives are utilized worldwide in pharmaceuticals, biotech, medical devices and diagnostics, and emerging chemical specialty applications.

JenKem Technology provides GMP grade PEG derivatives and bulk non-GMP orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. GMP manufacture of a wide range of high quality PEG derivatives is available from 200g to 40Kg or larger batches, following ICH Q7 guidelines under ISO 9001 and ISO 13485 certified quality management system.

JenKem Technology has filed DMFs for several PEG products, and has the capability to file other DMFs with the US FDA and China FDA at customers’ request.

PRODUCTS LISTED BY FUNCTIONAL GROUP

PEGs with ACRYLATE
PEGs with FLUORESCEIN
PEGs with PCL
PEGs with ALDEHYDE
PEGs with FMOC AMINE
PEGs with PHOSPHATE
PEGs with ALKYNE
PEGs with GALACTOSE
PEGs with PLA
PEGs with AMINE
PEGs with GLUCOSE
PEGs with PLGA
PEGs with AZIDE
PEGs with GLYCEROL
PEGs with PLL
PEGs with BENZYL
PEGs with HYDRAZIDE
PEGs with POLYGLUTAMIC ACID
PEGs with BIOTIN
PEGs with HYDROXYL
PEGs with QTX
PEGs with CARBOXYL
PEGs with IODOACETAMIDE
PEGs with SILANE
PEGs with CARBONATE
PEGs with ISOCYANATE
PEGs with SUCCINIMIDYL CARBONATE
PEGs with DBCO
PEGs with LIPOIC ACID
PEGs with TBOC AMINE
PEGs with DMG
PEGs with LMWP
PEGs with THIOL
PEGs with DSPE
PEGs with MALEIMIDE
PEGs with VA-PAB
PEGs with DTA
PEGs with NHS ESTER
PEGs with VC-PAB
PEGs with DTDA
PEGs with NORBORNENE
PEGs with VINYLSULFONE
PEGs with DTDPA
PEGs with NITROPHENYL CARBONATE
CUSTOM PEG PRODUCTS
PEGs with EPOXIDE
PEGs with OPSS
SMALL MOLECULE REAGENTS

 

Functionally, JenKem Technology’s PEG products include activated PEG derivatives for amine PEGylation, active PEG derivatives for N-terminal PEGylation, and activated PEG derivatives for thiol PEGylation, activated PEGs for carboxyl PEGylation, PEGs and small molecule reagents for Lipid Nanoparticles, PROTAC drugs, and ADCs, reagents for 3D printing, Click Chemistry, hydrogels, and many other applications.

PEG PRODUCTS BY APPLICATION
ACTIVATED PEGs FOR AMINE PEGYLATION
PEG LINKERS FOR ANTIBODY DRUG CONJUGATES (ADCs)
CLICK CHEMISTRY PEGS
ACTIVATED PEGs FOR C-TERMINAL PEGYLATION
PEGs FOR LIPID NANOPARTICLES (LNPs)
COPPER FREE CLICK CHEMISTRY PEGs
ACTIVATED PEGs FOR N-TERMINAL PEGYLATION
SMALL MOLECULES FOR LNPs
PEGs FOR HYDROGELS
ACTIVATED PEGs FOR THIOL PEGYLATION
PEGs FOR RNA DELIVERY
PEG CROSSLINKERS
CONTROLLED RELEASE DRUG DELIVERY
CELL PENETRATING PEPTIDE-PEGs
PEGs FOR SURFACE MODIFICATION
CUSTOM PEG CONJUGATES FOR DRUG DELIVERY
3D PRINTING REAGENTS
PEG CALIBRATION STANDARDS FOR GPC
PROTAC LINKERS AND E3 LIGASE LIGAND LINKER CONJUGATES
LOW TOXICITY PHOTOINITIATORS
BIODEGRADABLE PEG COPOLYMERS

Structurally, JenKem Technology’s PEG products include JenKem® proprietary Y-shape branched PEG derivatives; linear M-PEG derivatives with low diol content; homobifunctional PEG derivatives; heterobifunctional PEG derivatives; multi-arm homofunctional reactive PEGs for hydrogels; multi-arm heterofunctional PEG derivatives for ADC development; monodisperse / discrete PEGs; and biodegradable PEG copolymers with polyaminoacids, PLA, PLGA, PCL, and other polymers. PEG raw materials, which are PEGs with inactive hydroxyl groups, are provided in bulk in non-GMP grade. JenKem Technology’s PEG raw materials are manufactured in-house, back-integrated to production directly from ethylene oxide. GPC calibration standards, necessary for accurate GPC analysis of PEG products, are provided as GPC calibration kits for linear methoxy PEGs and 4arm PEGs.

JENKEM PEG PRODUCTS BY STRUCTURE
Y-SHAPE PEGs AND U-SHAPE PEGs
3ARM-PEG DERIVATIVES 
HETEROBIFUNCTIONAL LINEAR PEGs
DISCRETE MONODISPERSE PEGs
4ARM-PEG DERIVATIVES 
HETEROBIFUNCTIONAL MONODISPERSE PEGs
LINEAR METHOXY PEGs
6ARM-PEG DERIVATIVES 
LINEAR BENZYL PEG RAW MATERIALS
HOMOBIFUNCTIONAL PEGs
8ARM-PEG DERIVATIVES (HEXAGLYCEROL CORE)
LINEAR METHOXY PEG RAW MATERIALS
HOMOBIFUNCTIONAL MONODISPERSE PEGs
8ARM-PEG DERIVATIVES (TRIPENTAERYTHRITOL CORE)
MULTI-ARM PEG RAW MATERIALS
PEG CO-POLYMERS
HETEROBIFUNCTIONAL MULTI-ARM PEGs
CUSTOM PEG PRODUCTS

For inquiries on cGMP production of PEG derivatives please contact us at tech@jenkemusa.com. To place bulk PEG orders please contact us at sales@jenkemusa.com for a quotation.

For custom PEG synthesis of products with MW and functionalities different from our catalog selection below, custom PEGylated conjugates, and PEGylation services, please contact us at tech@jenkemusa.com.

JenKem PEGs

To learn about our extensive line of activated PEGs and PEG co-polymers and to place an online order directly with JenKem Technology for catalog PEGs, visit our online PEG catalog at https://www.jenkemusa.com/shop or contact us at sales@jenkemusa.com.

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7 guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.