JenKem Technology manufactures high quality activated PEG polymers, PEG co-polymers, and monodisperse PEGs, from laboratory to commercial scale. Our reactive polyethylene glycol derivatives are utilized worldwide in pharmaceuticals, biotech, medical devices and diagnostics, and emerging chemical specialty applications.
JenKem Technology provides GMP grade PEG derivatives and bulk non-GMP orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. GMP manufacture of a wide range of high quality PEG derivatives is available from 200g to 40Kg or larger batches, following ICH Q7 guidelines under ISO 9001 and ISO 13485 certified quality management system.
JenKem Technology has filed DMFs for several PEG products, and has the capability to file other DMFs with the US FDA and China FDA at customers’ request.
Functionally, JenKem Technology’s PEG products include activated PEG derivatives for amine PEGylation, active PEG derivatives for N-terminal PEGylation, and activated PEG derivatives for thiol PEGylation, activated PEGs for carboxyl PEGylation, PEGs and small molecule reagents for Lipid Nanoparticles, PROTAC drugs, and ADCs, reagents for 3D printing, Click Chemistry, hydrogels, and many other applications.
Structurally, JenKem Technology’s PEG products include JenKem® proprietary Y-shape branched PEG derivatives; linear M-PEG derivatives with low diol content; homobifunctional PEG derivatives; heterobifunctional PEG derivatives; multi-arm homofunctional reactive PEGs for hydrogels; multi-arm heterofunctional PEG derivatives for ADC development; monodisperse / discrete PEGs; and biodegradable PEG copolymers with polyaminoacids, PLA, PLGA, PCL, and other polymers. PEG raw materials, which are PEGs with inactive hydroxyl groups, are provided in bulk in non-GMP grade. JenKem Technology’s PEG raw materials are manufactured in-house, back-integrated to production directly from ethylene oxide. GPC calibration standards, necessary for accurate GPC analysis of PEG products, are provided as GPC calibration kits for linear methoxy PEGs and 4arm PEGs.
For inquiries on cGMP production of PEG derivatives please contact us at firstname.lastname@example.org. To place bulk PEG orders please contact us at email@example.com for a quotation.
For custom PEG synthesis of products with MW and functionalities different from our catalog selection below, custom PEGylated conjugates, and PEGylation services, please contact us at firstname.lastname@example.org.
To learn about our extensive line of activated PEGs and PEG co-polymers and to place an online order directly with JenKem Technology for catalog PEGs, visit our online PEG catalog at https://www.jenkemusa.com/shop or contact us at email@example.com.
Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7 guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.