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Discrete Monodisperse PEGs

JenKem Technology’s monodisperse PEG products are produced via very reproducible chemical reactions. Monodisperse / discrete PEGs lack the polydispersity of traditional PEG polymers. JenKem’s discrete PEGs retain the polyethylene glycol’s good solubility in water, offering to PEGylated drugs the same PEG benefits of reduced aggregation and immunogenicity, and increased hydrodynamic volume.

JenKem Technology’s catalog monodisperse PEG products consist of linear chains of five to twelve –CH2-CH2-O– units, and various terminal functional and reactive groups. Monodisperse PEG products with molecular weights up to 5000 Da, and possible larger, and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at tech@jenkemusa.com about pricing and availability of custom monodisperse PEGs.

JenKem Technology provides GMP grade PEG derivatives and bulk orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. JenKem Technology is capable of development and synthesis of a wide range of GMP monodisperse PEG derivatives starting at 200g up to 15 kg or greater batches, under ISO 9001 and ISO 13485 certified quality management system, following ICH Q7A guidelines. For inquiries on cGMP production of PEG derivatives please contact us at tech@jenkemusa.com.

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.

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