/Activated PEGs for Amine PEGylation

Activated PEGs for Amine PEGylation

JenKem Technology manufactures numerous PEGs for amine PEGylation. JenKem Technology’s NHS PEGs are categorized as PEG NHS Esters with stable linkers (such as Y-NHS, M-SCM, M-SPA, M-SBA, M-SHA, M-SGA, M-SSA, MPEG2 LYS NHS); PEGs with carbonate linker (such as M-SC); and degradable PEGs with cleavable NHS linker (such as M-SS and M-SG). JenKem Technology’s carboxy PEGs are more stable than M-PEG-SCM and can be activated. Sterically bulky Y-shape NHS PEGs facilitate the single point attachment to sterically available amines.

Amine PEGylation products with molecular weights, branching, and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at tech@jenkemusa.com about pricing and availability of custom activated PEGs for amine PEGylation.

JenKem Technology provides GMP grade PEG derivatives and bulk orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. JenKem Technology is capable of development and synthesis of a wide range of GMP PEG derivatives starting at 200g up to 40 kg or greater batches, under ISO 9001 and ISO 13485 certified quality management system, following ICH Q7A guidelines. For inquiries on cGMP production of PEG derivatives please contact us at tech@jenkemusa.com.

Linear NHS PEGs with Cleavable Linker

Linear Carbonate PEGs

Y-shaped Branched NHS PEGs with Stable Linker

U-shaped Branched NHS PEGs with Stable Linker

Linear Monosaccharide NHS PEGs with Stable Linker

Linear Methoxy NHS PEGs with Stable Linker

Y-shaped Branched Carboxy PEGs

Linear Carboxy PEGs

Linear Homobifunctional PEGs for Amine PEGylation

Linear Heterobifunctional PEGs Functionalized with Carboxyl or NHS

Multiarm Homofunctional PEGs Functionalized with Carboxyl or NHS

Multiarm Heterobifunctional PEGs Functionalized with Carboxyl or NHS

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.

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