AboutJenKemTianjin

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes in high-purity, low polydispersity polyethylene glycol (PEG) derivatives, PEG co-polymers, monodisperse PEGs, custom PEG derivative synthesis and PEGylation services. Specific strengths are supported by access to bulk ethylene oxide and the performance of all polymerizations and derivatizations in-house.

JenKem Technology supplies PEG derivatives worldwide, from R&D through GMP commercial quantities, for preclinical, clinical trials, and commercial products for pharma, biotech, medical devices, and diagnostics.

Capabilities

Development and manufacture of a wide range of PEG derivatives and PEG co-polymer derivatives with high purity and low polydispersity, in batch sizes of 1g to 40Kg or larger, under ISO 9001 and ISO 13485 certified Quality Management System, following ICH Q7 guidelines for GMP manufacture. Large scale and GMP manufacturing offered on a made-to-order basis, with flexibility to match customers’ specifications.

Controlled manufacture of raw polyethylene glycol polymers via polymerization of ethylene oxide, with annual capacity in the order of tons of high quality raw PEGs, which enables facile traceability for PEG derivatives manufacture from these raw materials. Current PEG raw materials plant has come on stream in 2017 which also has the capability of the purification of these raw PEGs under GMP conditions if needed for even higher quality products, and a new plant will be operational in 2023.

Custom synthesis of activated and raw PEGs: Y-Shaped, Linear Methoxy, Homobifunctional, Heterobifunctional, Multi-arm and Multi-arm Heterobifunctional, Monodisperse (Discrete) PEGs, Biodegradable PEG Co-Polymers such as PEG-PLGA, PEG-PLA, PEG-PCL, and other block co-polymers, and PEG GPC Standards.

Custom PEGylation of proteins, peptides, oligonucleotides, and small molecules; and conjugation of PEGs to other polymer systems.

Online ordering of  JenKem® catalog PEG products is available on our website, with global distribution of JenKem® PEG products direct from JenKem Technology China facilities. Many research grade PEG derivatives are sold through a collaboration with MilliporeSigma, listed in their catalog and on their website and identified as being a product of JenKem Technology.

Intellectual Property
      • JenKem Technology respects the intellectual property of others
      • As of July 2023, JenKem Technology has 116 patent approvals, 80 pending patent applications, several DMFs filed with the FDA, and many other innovative technologies under development
      • Several innovative PEG and PEGylation-related technologies patented by JenKem Technology are available for out-licensing
      • JenKem Technology has filed DMFs for several of its PEG products, and has the capability to file other DMFs with the US FDA and China FDA at customers’ request
Locations

JenKem Technology Tianjin – Site for commercial scale GMP manufacture of PEG derivatives, small scale PEG production, and R&D

JenKem_GMP_PEG_Synthesis

      • Plant in Tianjin, China came on stream in 2013
      • Audited by numerous multi-national pharma, biotech, and medical device companies for commercial-scale PEG manufacture
      • Located in the established Tianjin Economic-Technological Development Area (TEDA), a thriving area with globally recognized companies

JenKem Technology Liaoning – Facility for PEG raw materials manufacture and back-up GMP manufacture of PEG derivatives

      • Located in the Liaoning province
      • Convenient access to ethylene oxide raw material for PEG raw material production
      • Back-up facility for GMP production
      • First plant in Panjin, China came on stream in 2017
      • A second Liaoning site for GMP production with 6x-10x the capacity of the Tianjin facility is operational in 2023

JenKem Technology Beijing – Headquarters, R&D, PEGylation site

      • Located in New Northwest Territories Development Zone, Beijing, China
      • Part of Zhongguancun Science Park
      • Surrounded by numerous international companies
      • Sales and marketing for JenKem Technology’s customers located in mainland China

JenKem Technology USA – JenKem Technology’s international business office

      • Sales, business development, technical support, and marketing for JenKem Technology’s PEG and PEG co-polymer products, custom PEG synthesis, and PEGylation services
      • Serves all JenKem Technology’s customers located outside mainland China
      • Located in the Dallas, TX area
We warmly invite our customers to audit our facilities!