Activated Y-Shape PEGs

JenKem Technology provides branched PEG derivatives for amine pegylation (Y-NHS-40K), thiol pegylation (Y-MAL-40K), N-terminal PEGylation (Y-AALD-40K and Y-PALD-40K), fluorescent PEGs (Y-FITC-40K), and more. The sterically bulky structure of JenKem Technology’s proprietary Y-shape branched PEG derivatives, consisting of two linear methoxy PEG chains attached to a central core with an active group, may help to reduce the number of attachment sites to a protein molecule.

JenKem’s Y-shaped PEG derivatives are chemically purified during synthesis and are essentially free of activated bifunctional side products. For details on the applications of JenKem Technology Y-shape PEGs please visit

JenKem Technology Y-Shape PEGs with molecular weights and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at about a quotation on custom PEGs.

JenKem Technology provides GMP grade PEG derivatives and bulk orders via custom synthesis, offering the opportunity to match customers’ special quality requirements. JenKem Technology is capable of development and synthesis of a wide range of GMP PEG derivatives starting at 200g up to 40 kg or greater batches, under ISO 9001 and ISO 13485 certified quality management system, following ICH Q7A guidelines. For inquiries on cGMP production of PEG derivatives please contact us at

Y-shape PEG Derivatives

U-shaped Branched PEG Products

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.


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