Methoxy PEG Succinimidyl Glutarate with superior quality specification of ≥95% Substitution.
Methoxy PEG Succinimidyl Glutarate (Methoxy PEG SG) is a high quality amine reactive methyl ether NHS PEG product from JenKem Technology. Methoxy PEG SG is a degradable PEG with a cleavable ester linker between the PEG polymeric chain and the NHS ester. Linear NHS PEGs with a Cleavable Linker (degradable PEGs) are especially employed in controlled release drug development applications. Methoxy PEG Succinimidyl Glutarate reacts with the amine group of lysine(s) at pH 7-8, while the ester linkage is cleaved under regular ester cleaving reaction conditions. Methoxy PEG Succinimidyl Glutarate has a slightly longer hydrolysis half life compared to Methoxy PEG Succinimidyl Succinate. JenKem Technology offers Methoxy PEG SG with MW 5000 Da (M-SG-5000) and MW 20000 Da (M-SG-20K), in 1g and 10g packing sizes.
Different MW of Methoxy PEG Succinimidyl Glutarate products may be available by custom synthesis, please email us at firstname.lastname@example.org for details on custom PEGs. Other linear NHS esters are available – please select other cleavable linker NHS PEGs; or stable linker NHS PEGs. JenKem Technology provides repackaging services for an additional fee, please contact us if you require a different package size than our catalog selection.
Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for bulk pricing.
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1. Hutanu D, Frishberg MD, Guo L, Darie CC (2014) Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem appl 2:132. doi: 10.4172/2329-6798.1000132. Read about select applications of JenKem® PEGs in the medical device, drug development, and diagnostics areas, including drug delivery, wound healing, cell culture models, and tissue regeneration.
Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization directly from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.