Methoxy PEG Succinimidyl Butanoate for amine PEGylation with superior quality specification of ≥95% Substitution.
JenKem Technology’s Methoxy PEG Succinimidyl Butanoate (Methoxy PEG SBA) is a high quality amine reactive PEG product with a stable non-degradable linker between the PEG polymeric chain and the NHS ester. Methoxy PEG Succinimidyl Butanoate reacts with the amine group of lysine(s) such as amines on active ingredients of Mircera® or Peg-epo biosimilars, at room temperature at pH 7-8. Methoxy PEG Succinimidyl Butanoate has a longer hydrolysis half-life compared with M-PEG-SCM. JenKem Technology offers Methoxy PEG SBA with MW 20000 Da (M-SBA-20K), in 1g and 10g packing sizes.
Different MW of Methoxy PEG SBA products may be available by custom synthesis, please email us at email@example.com for details on custom PEGs. Other linear JenKem NHS ester PEGs are available – if interested please select stable linker NHS PEGs, carbonate linker stable NHS PEGs, or cleavable linker NHS PEGs. JenKem Technology provides repackaging services for an additional fee, please contact us if you require a different package size than our catalog selection.
Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for bulk pricing.
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1. Hutanu, D., et al., (2014) Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem appl 2:132. doi: 10.4172/2329-6798.1000132. Read about select applications of JenKem® PEGs in the medical device, drug development, and diagnostics areas, including drug delivery, wound healing, cell culture models, and tissue regeneration.
Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization directly from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.