Monodisperse Hydroxyl PEG9 Hydroxyl reagent with superior quality specification of ≥ 95% Purity.
Monodisperse Hydroxyl PEG9 Hydroxyl from JenKem Technology (single molecule PEG9 dihydroxyl, or Enneethylene glycol) is a homobifunctional PEG for PEGylation, with stable HO groups that can be activated. Monodisperse homobifunctional PEG derivatives from JenKem Technology are high quality crosslinkers for PEGylation of proteins and peptides, nanoparticle and surface modifications. Conjugation with homobifunctional PEGs provides an increased drug load compared to pegylation using linear PEGs. JenKem Technology’s monodisperse discrete PEG dihydroxy products are produced via very reproducible chemical reactions and lack the polydispersity of traditional PEG polymers. JenKem’s monodisperse dihydroxyl PEGs retain the polyethylene glycol’s good solubility in water, while offering to PEGylated drugs the same PEG benefits of reduced aggregation and immunogenicity, and increased hydrodynamic volume.
JenKem Technology offers monodisperse Hydroxyl PEG Hydroxyl with MW 370.5 Da (HO-PEG8-OH), MW 414.5 Da (HO-PEG9-OH), and MW 546.7 Da (HO-PEG12-OH) in 1g and 5g packing sizes. Dihydroxyl PEGs with different numbers of -CH2-CH2-O- units (different “n”) may be available by custom synthesis, please email us at firstname.lastname@example.org for details on custom PEGs. JenKem Technology provides repackaging services for an additional fee, please contact us if you require a different package size than our catalog selection. Bulk PEGs and GMP PEGs are also available upon request. Please contact us for special bulk pricing.
1. Hutanu D, et al., (2014) Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem appl 2:132. doi: 10.4172/2329-6798.1000132. Read about select applications of JenKem® PEGs in the medical device, drug development, and diagnostics areas, including drug delivery, wound healing, cell culture models, and tissue regeneration.
Founded in 2001 by recognized experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to on-site manufacturing from ethylene oxide, enabling facile traceability for GMP regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.