PEG Azide

JenKem Technology offers large scale GMP manufacture of PEG derivatives for copper-catalyzed and copper-free Click Chemistry.

Kilogram scale manufacture (5Kg per batch and more) of PEG and Monodisperse PEG Azide Derivatives with high purity (95%), in both GMP and non-GMP grade is not available.

PEG azide derivatives are suitable as click chemistry reagents for reaction with alkynes. Click chemistry has found widespread application in bioconjugation in the pharmaceutical and biotech industry. Click reactions are rapid, quantitative, have high efficiency and stereo selectivity, and few or no by-products under mild reaction conditions.

Several examples of scaled-up PEG azide products are listed below, and other products with may be made-to-order. Please contact us at for more information.

Item Number

Molecular Weight Range
M-PEGn-AZIDE Monodisperse PEG (n = 6 to 24 or higher)
M-PEG-AZIDE 1000Da-20KDa


In addition to PEG Azides and PEG Alkynes, JenKem Technology is specialized in large scale manufacture of PEG products for Copper-Free Click Chemistry.

JenKem Technology’s PEG DBCO derivatives have good water solubility compared to cyclooctynes, and better biocompatibility and no cytotoxicity as compared to traditional click reagents. JenKem Technology has increased its capability to provide high quality PEG Dibenzocyclooctyne (DBCO) products in large kilogram-scale and above, in both non-GMP and GMP grade, at very affordable prices. PEG DBCO

Below are several examples of PEG DBCO products manufactured by JenKem Technology. PEG and monodisperse PEG DBCO derivatives with different branching, MW, and functionalities may be available by custom synthesis.

Methoxy PEG DBCO Products
Item Number Item Description
M-DBCO-2000 Methoxy PEG Dibenzocyclooctyne, MW 2000
M-DBCO-3500 Methoxy PEG Dibenzocyclooctyne, MW 3500
M-DBCO-5000 Methoxy PEG Dibenzocyclooctyne, MW 5000
M-DBCO-10K Methoxy PEG Dibenzocyclooctyne, MW 10000
M-DBCO-20K Methoxy PEG Dibenzocyclooctyne, MW 20000
M-DBCO-30K Methoxy PEG Dibenzocyclooctyne, MW 30000
M-DBCO-40K Methoxy PEG Dibenzocyclooctyne, MW 40000
Y-Shaped and U-Shaped PEG DBCO Products
Item Number Item Description
Y-DBCO-40K Y-shape (MPEG20K)2 Dibenzocyclooctyne, MW 40000
MPEG2-DBCO-40K MPEG2 Dibenzocyclooctyne, MW 40000
Homobifunctional PEG DBCO Products
Item Number Item Description
DBCO-PEG2000-DBCO PEG (Dibenzocyclooctyne)2, MW 2000
DBCO-PEG5000-DBCO PEG (Dibenzocyclooctyne)2, MW 5000
DBCO-PEG10K-DBCO PEG (Dibenzocyclooctyne)2, MW 10000
Multi-arm PEG DBCO Products
Item Number Item Description
4ARM-DBCO-10K 4arm PEG Dibenzocyclooctyne (pentaerythritol), MW 10000
4ARM-DBCO-20K 4arm PEG Dibenzocyclooctyne (pentaerythritol), MW 20000
8ARM(TP)-DBCO-10K 8arm PEG Dibenzocyclooctyne (tripentaerythritol), MW 10000
8ARM(TP)-DBCO-20K 8arm PEG Dibenzocyclooctyne (tripentaerythritol), MW 20000
8ARM(TP)-DBCO-40K 8arm PEG Dibenzocyclooctyne (tripentaerythritol), MW 40000
Heterobifunctional PEG DBCO Products
Item Number Item Description
DBCO-PEG2000-SCM Dibenzocyclooctyne PEG Succinimidyl Carboxymethyl Ester, MW 2000
DBCO-PEG3500-SCM Dibenzocyclooctyne PEG Succinimidyl Carboxymethyl Ester, MW 3500
DBCO-PEG5000-SCM Dibenzocyclooctyne PEG Succinimidyl Carboxymethyl Ester, MW 5000
DBCO-PEG2000-NH2TFA Dibenzocyclooctyne PEG Amine, TFA Salt, MW 2000
DBCO-PEG3500-NH2TFA Dibenzocyclooctyne PEG Amine, TFA Salt, MW 3500
DBCO-PEG5000-NH2TFA Dibenzocyclooctyne PEG Amine, TFA Salt, MW 5000
DBCO-PEG2000-MAL Dibenzocyclooctyne PEG Maleimide, MW 2000
DBCO-PEG3500-MAL Dibenzocyclooctyne PEG Maleimide, MW 3500
DBCO-PEG5000-MAL Dibenzocyclooctyne PEG Maleimide, MW 5000
DBCO-PEG2000-OH Dibenzocyclooctyne PEG Hydroxyl, MW 2000
DBCO-PEG3500-OH Dibenzocyclooctyne PEG Hydroxyl, MW 3500
DBCO-PEG5000-OH Dibenzocyclooctyne PEG Hydroxyl, MW 5000
DBCO-PEG2000-OPSS Dibenzocyclooctyne PEG OPSS, MW 2000
DBCO-PEG3500-OPSS Dibenzocyclooctyne PEG OPSS, MW 3500
DBCO-PEG5000-OPSS Dibenzocyclooctyne PEG OPSS, MW 5000


Please contact us at for a quotation and more information about our PEG products for Copper-Free Click Chemistry and to inquire about related products not mentioned on this page.

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7 guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.