Fmoc Amine PEG Acetic Acid

$375.00$1,500.00

PEG products with additional MW may be made to order, please contact us for details

Description

High quality Fmoc Amine PEG Acetic Acid with standard quality specification of ≥95% Substitution.

Heterobifunctional FMOC (Fluorenylmethyloxycarbonyl) Amine PEG Acetic Acid products with protected amine from JenKem Technology are generally employed as crosslinking agents or as spacers between two different chemical entities. The PEG moiety in the heterobifunctional PEG derivatives provides water solubility, biocompatibility, and flexibility. Applications are especially geared towards the development of antibody drug conjugates (ADC’s).

Heterobifunctional PEGylation reagents with molecular weights, branching, and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at tech@jenkemusa.com about pricing and availability of custom PEGs.

Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for bulk pricing.

Click here to download the MSDS

References:

1. Veiman, K.-L., et al., PEG shielded MMP sensitive CPPs for efficient and tumor specific gene delivery in vivo, Journal of Controlled Release, 2015, 209: 238-247.

2. Guarnieri, D., et al., Tumor‐activated prodrug (TAP)‐conjugated nanoparticles with cleavable domains for safe doxorubicin delivery, Biotechnology and Bioengineering, 2015, 112(3): 601-611.

3. Kuo, C.-H., Inhibition of atherosclerosis-promoting microRNAs via targeted polyelectrolyte complex micelles J. Mater. Chem. B, 2014, 2, 8142-8153.

Note: Starting July 2016, Fmoc Amine PEG Acetic Acid is the new name of the product Fmoc Amine PEG Carboxyl(MW 2000 (FMOC-PEG2000-COOH), MW 3500 (FMOC-PEG3500-COOH), MW 5000 (FMOC-PEG5000-COOH) and MW 7500 (FMOC-PEG7500-COOH)). JenKem Technology has revised the name of the product to better reflect the chemical structure, as many other PEG derivatives with a COOH group are offered in the 2016 JenKem USA catalog.

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.

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