3D Printing of PEG Hydrogel Scaffolds Using Novel Low Toxicity Photoinitiator abstract from JenKem Technology was accepted at the 2018 SFB meeting for presentation in poster #540.
3D printing biomaterials require biocompatibility, porosity, biodegradability and good adhesion. PEG hydrogels meet these specifications, and in particular PEG acrylate (PEG-ACLT) derivatives are widely applied in hydrogel formation via photopolymerization. Currently, small molecule photoinitiators have a certain level of cytotoxicity, and low water solubility.
We have developed a novel photoinitiator (M-QTX) that exhibits good water solubility and low cytotoxicity. Using this photoinitiator, PEG-ACLT hydrogels can be 3D printed through stereolithography into well-defined transparent three-dimensional stereograms with low toxicity and good biocompatibility.
Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.