Methoxy PEG5 Thiol


PEG products with additional MW may be made to order, please contact us for details


Monodisperse Methoxy PEG5 Thiol reagent with superior quality specification of ≥ 90% Purity.

JenKem Technology manufactures high quality monodisperse Methoxy PEG Thiol products for thiol PEGylation in mild conditions. The thiol group can react with metal surfaces, other thiols, disulfide, maleimide, and vinyl sulfone groups. JenKem Technology’s monodisperse discrete PEG products are produced via very reproducible chemical reactions and lack the polydispersity of traditional PEG polymers. JenKem’s monodisperse PEGs retain the polyethylene glycol’s good solubility in water, while offering to PEGylated drugs the same PEG benefits of reduced aggregation and immunogenicity, and increased hydrodynamic volume.

JenKem Technology offers monodisperse Methoxy-PEG5-Thiol (MW 268.4 Da) and  Methoxy-PEG6-Thiol (MW 312.4 Da), in 1g and 5g packing sizes. Monodisperse Methoxy-PEG4-Thiol (M-PEG4-SH), Methoxy-PEG7-Thiol (M-PEG7-SH), Methoxy-PEG9-Thiol (M-PEG9-SH) and Methoxy-PEG12-Thiol (M-PEG12-SH) and monodisperse methoxy thiol PEGs with different MW (different number of -CH2-CH2-O- units) may be made-to-order, please email us at for details on custom PEGs.

JenKem Technology provides repackaging services for an additional fee, please contact us if you require a different package size than our catalog selection. Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for special bulk pricing.


1. Mei, L., et al., Increased tumor targeted delivery using a multistage liposome system functionalized with RGD, TAT and cleavable PEG, International Journal of Pharmaceutics, 2014, 468(1–2): p. 26-38.

2. Hutanu D, et al., Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives, Mod Chem appl, 2014, 2:132. doi: 10.4172/2329-6798.1000132. Read about select applications of JenKem® PEGs in the medical device, drug development, and diagnostics areas, including drug delivery, wound healing, cell culture models, and tissue regeneration.

Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom polymer synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.

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