Please contact us at firstname.lastname@example.org to place an order for (MAL)3-4ARMPEG-NHS, high quality linker for ADCs.
(MAL)3-4ARMPEG-NHS (4arm PEG, 1arm-NHS, 3arm-Maleimide) with various MW from JenKem Technology is a high quality 4arm heterobifunctional PEG product. JenKem Technology’s patented multi-arm heterofunctional PEG derivatives are designed as linkers for Antibody-Drug Conjugates (ADCs), as they facilitate the coupling of high ratios of drug molecules per antibody. ADCs conjugated via multiarm PEGs deliver a higher concentration of drugs to targets for each antibody-antigen interaction, and exhibit improved solubility and PK/PD profile.
Multi-arm Heterofunctional PEG products with molecular weights and functional groups not listed in our online catalog may be available by custom synthesis. Please inquire at email@example.com about pricing and availability.
Bulk PEGs and GMP grade PEGs are made-to-order. Please contact us for bulk pricing.
1. Hutanu D, Frishberg MD, Guo L, Darie CC (2014) Recent Applications of Polyethylene Glycols (PEGs) and PEG Derivatives. Mod Chem appl 2:132. doi: 10.4172/2329-6798.1000132. Read about select applications of JenKem® PEGs in the medical device, drug development, and diagnostics areas, including drug delivery, wound healing, cell culture models, and tissue regeneration.
Founded in 2001 by experts in PEG synthesis and PEGylation, JenKem Technology specializes exclusively in the development and manufacturing of high quality polyethylene glycol (PEG) products and derivatives, and related custom synthesis and PEGylation services. JenKem Technology is ISO 9001 and ISO 13485 certified, and adheres to ICH Q7A guidelines for GMP manufacture. The production of JenKem® PEGs is back-integrated to in-house polymerization from ethylene oxide, enabling facile traceability for regulated customers. JenKem Technology caters to the PEGylation needs of the pharmaceutical, biotechnology, medical device and diagnostics, and emerging chemical specialty markets, from laboratory scale through large commercial scale.