/References for JenKem Technology’s PEG Products

References for JenKem Technology’s PEG Products

References for JenKem Technology’s PEG Products 2019-01-17T13:31:54+00:00

To learn about the applications of JenKem® PEGs for PEGylation of therapeutics, drug delivery, medical devices hydrogels, diagnostics, and more, we invite you to visit our website, and consult references for each individual product listed on the pages below:

A few select publications citing the use of JenKem® high quality PEG products, are listed on the pages below by publication date:

Jingna Zhang, Xiaoyuan Ma, Zhouping Wang, Real-time and in-situ monitoring of Abrin induced cell apoptosis by using SERS spectroscopy, Talanta, Volume 195, 2019, Pages 8-16; Keywords: SERS; AuNSs; Abrin; Cell apoptosis; mPEG-SH

J.R. Eles, A.L. Vazquez, T.D.Y. Kozai, X.T. Cui, Meningeal inflammatory response and fibrous tissue remodeling around intracortical implants: An in vivo two-photon imaging study, Biomaterials, Volume 195, 2019, Pages 111-123;  Keywords: Intravital imaging; Neural interface; Foreign body response; Hydrogel; Meninges; Brain-computer interface; 4-arm poly(ethylene) glycol

Jenny Wang, Samuel Yang, Kelly Zhang, Multi-arm PEG-maleimide conjugation intermediate characterization and hydrolysis study by a selective HPLC method, Journal of Pharmaceutical and Biomedical Analysis, Volume 164, 2019, Pages 452-459; Keywords: Polyethylene glycol (PEG); Maleimide; Multi-arm polymer; Conjugation; Maleimide hydrolysis; Method development; 8-arm PEG-maleimide

Courtney M. Dumont, Mitchell A. Carlson, Mary K. Munsell, Andrew J. Ciciriello, Katerina Strnadova, Jonghyuck Park, Brian J. Cummings, Aileen J. Anderson, Lonnie D. Shea, Aligned hydrogel tubes guide regeneration following spinal cord injury, Acta Biomaterialia, 2019; Keywords: Modular biomaterial; Tissue repair; Spinal cord injury; Axon elongation; 8-arm PEG maleimide

Alanod D. AlQahtani, Layla Al-mansoori, Sara S. Bashraheel, Fatma B. Rashidi, Afrah Al-Yafei, Philip Elsinga, Alexander Domling, Sayed K. Goda, Production of “biobetter” glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment, European Journal of Pharmaceutical Sciences, Volume 127, 2019, Pages 79-91; Keywords: Carboxypeptidase G2; CPG2; Antibody directed enzyme prodrug therapy; ADEPT; PEGylation; Human serum albumin; HSA; HSA-glucarpidase; PEGylated glucarpidase; Cancer; Y-shaped (MPEG20K)2 succinimidyl carboxymethyl ester

Matthew B. Coppock, Margaret Hurley, Curtis Jones, Daniela Erickson, Dimitra N. Stratis-Cullum, A novel discovery, maturation, and assay integration approach for the development of ruggedized multi-valent capture receptors exemplified against the chikungunya virus E2 protein, Sensing and Bio-Sensing Research, Volume 22, 2019, 100248; Keywords: Capture agent; Chikungunya; Peptide; click chemistry; In silico; Biological assay; 4-arm (1-arm-Amine, 3-arm-Azide), TFA salt

Rajkumar S., Prabaharan M., Multi-functional core-shell Fe3O4@Au nanoparticles for cancer diagnosis and therapy, Colloids and Surfaces B: Biointerfaces, Volume 174, 2019, Pages 252-259; Keywords: Multi-functional; Core-shell nanoparticles; Theranostics; Cancer therapy; Drug delivery; NHS-PEG-maleimide; NHS-mPEG

Hojung Kwak, Sungchul Shin, Hyunji Lee, Jinho Hyun, Formation of a keratin layer with silk fibroin-polyethylene glycol composite hydrogel fabricated by digital light processing 3D printing, Journal of Industrial and Engineering Chemistry, 2018; Keywords: Digital light processing; 3D printing; 4-arm polyethylene glycol acrylate; Silk fibroin; Keratin; 4-arm PEG-hydroxyl

Weijun Xu, Junmin Qian, Guanghui Hou, Yaping Wang, Jinlei Wang, Tiantian Sun, Lijie Ji, Aili Suo, Yu Yao, PEGylated hydrazided gold nanorods for pH-triggered chemo/photodynamic/photothermal triple therapy of breast cancer, Acta Biomaterialia, Volume 82, 2018, Pages 171-183; Keywords: Gold nanorods; PEGylation; Triple therapy; Photodynamic and photothermal therapy; pH-responsiveness; mPEG-SH

Colin G. Buss, Jaideep S. Dudani, Reid T.K. Akana, Heather E. Fleming, Sangeeta N. Bhatia, Protease activity sensors noninvasively classify bacterial infections and antibiotic responses, EBioMedicine, Volume 38, 2018, Pages 248-256; Keywords: Protease; Nanoparticle; Diagnostic; Bacterial pneumonia; 8-arm PEG-MAL

Wu-Cheng Nie, Fei Song, Qian Xiao, Jiao-Jiao Liu, Xiao-Hui Wang, Jiang-Ling Zhou, Si-Chong Chen, Xiu-Li Wang, Yu-Zhong Wang, Orthogonal construction of dual dynamic covalent linkages toward an “AND” logic-gate acid-/salt-responsive block copolymer, Polymer, 2018, Volume 159, Pages 32-38; Keywords: Block copolymer; Dynamic boronate ester; BN/BO interaction; mPEG-NH2

Tianqun Lang, Xinyue Dong, Zhong Zheng, Yiran Liu, Guanru Wang, Qi Yin, Yaping Li, Tumor microenvironment-responsive docetaxel-loaded micelle combats metastatic breast cancer,Science Bulletin, 2018; Keywords: Breast cancer; Dual-sensitive micelle; Metastasis; Tumor-targeting; mPEG-NH2

Di Gao, Pui-Chi Lo, Polymeric micelles encapsulating pH-responsive doxorubicin prodrug and glutathione-activated zinc(II) phthalocyanine for combined chemotherapy and photodynamic therapy, Journal of Controlled Release, Volume 282, 2018, Pages 46-61; Keywords: Chemotherapy; Photodynamic therapy; Doxorubicin; Phthalocyanine; Polymeric micelles; Methoxypolyethylene glycol amine

Hongliang He, Quan Yuan, Jinghua Bie, Ryan L. Wallace, Paul J. Yannie, Jing Wang, Michael G. Lancina, Olga Yu Zolotarskaya, William Korzun, Hu Yang, Shobha Ghosh, Development of mannose functionalized dendrimeric nanoparticles for targeted delivery to macrophages: use of this platform to modulate atherosclerosis, Translational Research, Volume 193, 2018, Pages 13-30; Keywords: Mannose-PEG-NHS

Sanaz Javanmardi, Ali Mohammad Tamaddon, Mahmoud Reza Aghamaali, Ladan Ghahramani, Samira Sadat Abolmaali, Redox-Sensitive, PEG-Shielded Carboxymethyl PEI Nanogels Silencing MicroRNA-21, Sensitizes Resistant Ovarian Cancer Cells to Cisplatin, Asian Journal of Pharmaceutical Sciences, 2018; Keywords: MicroRNA; PEI nanogels, Anti-miR-21; Gene delivery; Cisplatin resistance; Methoxy polyethylene glycol COOH

Connor J. Balzer, Andrew R. Wagner, Luke A. Helgeson, Brad J. Nolen, Dip1 Co-opts Features of Branching Nucleation to Create Linear Actin Filaments that Activate WASP-Bound Arp2/3 Complex, Current Biology, Volume 28, Issue 23, 2018, Pages 3886-3891.e4; Keywords: Arp2/3 complex; Dip1; actin; S. pombe; endocytosis; Wsp1; WASP; Biotin-PEG NHS

James R. Day, Anu David, Jiwon Kim, Evan A. Farkash, Marilia Cascalho, Nikola Milašinovi, Ariella Shikanov, The impact of functional groups of poly(ethylene glycol) macromers on the physical properties of photo-polymerized hydrogels and the local inflammatory response in the host, Acta Biomaterialia, Volume 67, 2018, Pages 42-52; Keywords: Poly(ethylene glycol); Photo-polymerization; Functional groups; RGD modification; Inflammatory response; multi-arm PEG-VS, PEG-Acrylate and PEG-Mal

Anbu Mozhi, Israr Ahmad, Qari Muhammad Kaleem, Ruslan G. Tuguntaev, Ahmed Shaker Eltahan, Chen Wang, Rong Yang, Chan Li, Xing-Jie Liang, Nrp-1 receptor targeting peptide-functionalized TPGS micellar nanosystems to deliver 10-hydroxycampothecin for enhanced cancer chemotherapy,International Journal of Pharmaceutics, Volume 547, Issues 1–2, 2018, Pages 582-592; Keywords: Mitochondria; Reactive oxygen species; 10-hydroxycamptothecin; Peptide; Topoisomerase I enzyme; Mal-PEG-OH

Alibolandi, M., et al., Curcumin-entrapped MUC-1 aptamer targeted dendrimer-gold hybrid nanostructure as a theranostic system for colon adenocarcinoma, International Journal of Pharmaceutics, V. 549 (1–2), 2018, P. 67-75. Keywords: PAMAM; Curcumin; Colorectal cancer; Theranostic; CT scan; MAL-PEG-COOH 

Behi, J., et al., Optimization of PEGylation reaction time and molar ratio of rhG-CSF toward increasing bioactive potency of monoPEGylated protein, International Journal of Biological Macromolecules, V. 109, 2018, P. 888-895. Keywords: Methoxy polyethylene glycol propionaldehyde (mPEG-ALD) ; rhG-CSF; PEGylation; Characterization; Purity; Biological activity

Li, F., et al., Cartilage tissue formation through assembly of microgels containing mesenchymal stem cells, Acta Biomaterialia, V. 77, 2018, P. 48-62. Keywords: 4-arm PEG-Succinimidyl Glutaramide;  Cartilage tissue engineering; Microgels; Mesenchymal stem cells; Cell encapsulation

Umerska, A., at al., Freeze drying of polyelectrolyte complex nanoparticles: Effect of nanoparticle composition and cryoprotectant selection, International Journal of Pharmaceutics, V. 552 (1–2), 2018, P. 27-38. Keywords: Four-arm branched PEG; Polyelectrolyte complex nanoparticle; Freeze drying; Hyaluronate; Chitosan; Chondroitin; Protamine

Jansen, L.E., et al., Control of thiol-maleimide reaction kinetics in PEG hydrogel networks, Acta Biomaterialia, V. 70, 2018, P. 120-128. Keywords:  4-arm PEG-maleimide ; Biomaterials; Tissue engineering; Michael-type addition reaction; Peptides

Nguyen, M.K., et al., RNA interfering molecule delivery from in situ forming biodegradable hydrogels for enhancement of bone formation in rat calvarial bone defects, Acta Biomaterialia, V. 75, 2018, P. 105-114. Keywords: 8-arm-PEG-SH ; RNAi; Hydrogel; hMSC; Bone regeneration

Peng, G., at al., N-terminal site-specific PEGylation enhances the circulation half-life of Thymosin alpha 1, Journal of Drug Delivery Science and Technology, 2018. Keywords: mPEG-SH

Pereira Gomes, C., et al., Fine tuning neuronal targeting of nanoparticles by adjusting the ligand grafting density and combining PEG spacers of different length, Acta Biomaterialia, V. 78, 2018, P. 247-259. Keywords: MeO-PEG-MAL ; Nanoparticle surface modification/functionalization; PEGylation; Targeted nanoparticles; Spacer length; Cellular uptake

Faust, H.J., et al., A hyaluronic acid binding peptide-polymer system for treating osteoarthritis, Biomaterials, V. 183, 2018, P. 93-101. Keywords: Biotin-PEG-thiol  Osteoarthritis; Hyaluronic acid; Peptide-polymer; Anterior cruciate ligament; Cartilage; Hyaluronic acid binding peptide

Jones, S.K., et al., Correlating quantitative tumor accumulation and gene knockdown using SPECT/CT and bioluminescence imaging within an orthotopic ovarian cancer model, Biomaterials, V. 178, 2018, P. 183-192. Keywords: MPEG raw material; Folate receptor alpha; Folate receptor targeting; siRNA delivery; Polymer micelleplexes; Ovarian cancer; Ovarian cancer xenograft

Kushwah, V., et al., Implication of linker length on cell cytotoxicity, pharmacokinetic and toxicity profile of gemcitabine-docetaxel combinatorial dual drug conjugate, International Journal of Pharmaceutics, V. 548 (1), 2018, P. 357-374. Keywords:  NH2-PEG-COOH ; Docetaxel; Gemcitabine; Dual drug delivery; Bio-conjugation; Linker screening; Prodrug

Jiang, Y., et al., TEMPO-oxidized starch nanoassemblies of negligible toxicity compared with polyacrylic acids for high performance anti-cancer therapy, International Journal of Pharmaceutics, V. 547(1–2), 2018, P. 520-529. Keywords:  Maleimide PEG amine ; Nanoassemblies; TEMPO-oxidized starch polymer; Targeted delivery; Cancer therapy; DOX

Chen, G., et al., NIR-induced spatiotemporally controlled gene silencing by upconversion nanoparticle-based siRNA nanocarrier, Journal of Controlled Release, V. 282, 2018, P. 148-155. Keywords: Maleimide–PEG–NH2 ; Spatiotemporally controlled gene silencing; NIR-controlled release; Upconversion nanoparticle; Host–guest interaction

Yang, J., et al., A positron emission tomography image-guidable unimolecular micelle nanoplatform for cancer theranostic applications, Acta Biomaterialia, V. 79, 2018, P. 306-316. Keywords: Maleimide PEG Amine and Methoxy-PEG-NH2 ; Unimolecular micelles; Cancer targeting; Nucleolin; Selective drug release; Nuclear imaging

Gao, M., et al., All-active antitumor micelles via triggered lipid peroxidation, Journal of Controlled Release, V. 286, 2018, P. 381-393. Keywords: mPEG-NH2 ; Micelles; All-active; Fatty acid; Self-assembly; Lipid peroxidation

Jia, H.R., et al., Plasma membrane-anchorable photosensitizing nanomicelles for lipid raft-responsive and light-controllable intracellular drug delivery, Journal of Controlled Release, V. 286, 2018, P. 103-113. Keywords: Methoxyl PEG amine (OMe-PEG-NH2) ; Plasma membrane-responsive nanoparticles; PDT; Intracellular delivery; Endosomal/lysosomal entrapment; Cell surface engineering

Zhang, Y., et al., Endogenous albumin-mediated delivery of redox-responsive paclitaxel-loaded micelles for targeted cancer therapy, Biomaterials, V. 183, 2018, P. 243-257. Keywords: Methoxy PEG azide (MeO-PEG-N3) and Mal-PEG-NHS ; Albumin; ABD035; Tumor homing; SPARC; Micelles; Redox-responsive

Rajkumar, S., et al., Multi-functional nanocarriers based on iron oxide nanoparticles conjugated with doxorubicin, poly(ethylene glycol) and folic acid as theranostics for cancer therapy, Colloids and Surfaces B: Biointerfaces, V. 170, 2018, P. 529-537. Keywords: Methoxy PEG-NHS and NHS-PEG-maleimide ; Nanocarriers; Multi-functional; Theranostics; Tumor-targeted; Drug delivery

Kushwah, V., at al., Improved antitumor efficacy and reduced toxicity of docetaxel using anacardic acid functionalized stealth liposomes, Colloids and Surfaces B: Biointerfaces, V. 172, 2018, P. 213-223. Keywords: PEG bis-amine ; Docetaxel; Anacardic acid; VEGF receptor; Functionalized liposome; Angiogenesis

Meng, Y., et al., Aminopeptidase N (CD13) targeted MR and NIRF dual-modal imaging of ovarian tumor xenograft, Materials Science and Engineering: C, V. 93, 2018, P. 968-974. Keywords: Polyethylene glycol diamine (H2N–PEG–NH2)

Liying Wang, Minfeng Huo, Yu Chen, Jianlin Shi, Iron-engineered mesoporous silica nanocatalyst with biodegradable and catalytic framework for tumor-specific therapy, Biomaterials, Volume 163, 2018, Pages 1-13, Keywords: M-SLN; Framework engineering; Catalytic nanomedicine; Fenton-like reaction; Tumor microenvironment; Coordination degradation

Hung-Yi Liu, Murray Korc, Chien-Chi Lin, Biomimetic and enzyme-responsive dynamic hydrogels for studying cell-matrix interactions in pancreatic ductal adenocarcinoma, Biomaterials, Volume 160, 2018, Pages 24-36, Keywords: PEG4SH.  Pancreatic ductal adenocarcinoma; Dynamic hydrogel; Matrix stiffness; Hyaluronic acid; Epithelial-mesenchymal transition

Fang Zhou, Meiling Wen, Peiqiong Zhou, Yunhui Zhao, Xiaoling Jia, Yubo Fan, Xiaoyan Yuan, Electrospun membranes of PELCL/PCL-REDV loading with miRNA-126 for enhancement of vascular endothelial cell adhesion and proliferation, Materials Science and Engineering: C, Volume 85, 2018, Pages 37-46, Keywords: MAL-PEG-NHS; PELCL; REDV peptide; miRNA-126; Electrospun membranes; Vascular endothelial cells

Luodan Yu, Yu Chen, Han Lin, Wenxian Du, Hangrong Chen, Jianlin Shi, Ultrasmall mesoporous organosilica nanoparticles: Morphology modulations and redox-responsive biodegradability for tumor-specific drug delivery, Biomaterials, Volume 161, 2018, Pages 292-305, Keywords: Me-PEG-Silane ; Mesoporous organosilica; Reduction-responsive biodegradation; Drug delivery; Nanomedicine; Cancer therapy

Allison Post, Alysha P. Kishan, Patricia Diaz-Rodriguez, Egemen Tuzun, Mariah Hahn, Elizabeth Cosgriff-Hernandez, Introduction of sacrificial bonds to hydrogels to increase defect tolerance during suturing of multilayer vascular grafts, Acta Biomaterialia, Volume 69, 2018, Pages 313-322, Keywords: Acrylate-PEG-NHS; Hydrogel; Suture damage resistance; Sacrificial bonds; Vascular graft; Thromboresistant coating

Huiying Li, Honghao Zheng, Yixian Zhang, Wenbo Zhang, Weijun Tong, Changyou Gao, Preparation of photo-responsive poly(ethylene glycol) microparticles and their influence on cell viability, Journal of Colloid and Interface Science, Volume 514, 2018, Pages 182-189, Keywords: 8arm-PEG-NH2; Polyethylene glycol; Ortho-nitrobenzyl; Cellular uptake; Photo-responsive particles

Tao Yang, David W.M. Marr, Ning Wu, Superparamagnetic colloidal chains prepared via Michael-addition, Colloids and Surfaces A: Physicochemical and Engineering Aspects, Volume 540, 2018, Pages 23-28, Keywords: 4arm-PEG-maleimide; Superparamagnetic chains; Thiol-maleimide Michael addition; Stability; Flexibility

Kuo-Ming Yu, Johnson Yiu-Nam Lau, Manson Fok, Yuk-Keung Yeung, Siu-Ping Fok, Suxing Zhang, Peizhen Ye, Kezhi Zhang, Xiaobo Li, Juan Li, Qin Xu, Wing-Tak Wong, Qui-Lim Choo, Preclinical evaluation of the mono-PEGylated recombinant human interleukin-11 in cynomolgus monkeys, Toxicology and Applied Pharmacology, Volume 342, 2018, Pages 39-49, Keywords: Y-shaped PEG aldehyde; PEGylated; IL-11; Toxicology; Preclinical; Monkeys; Interleukin

Junxiao Ye, Xing Pei, Hui Cui, Zhili Yu, Hyukjin Lee, Jianxin Wang, Xu Wang, Lu Sun, Huining He, Victor C. Yang, Cellular uptake mechanism and comparative in vitro cytotoxicity studies of monomeric LMWP-siRNA conjugate, Journal of Industrial and Engineering Chemistry, 2018, Keywords: NHS-PEG-OPSS; Cell penetrating peptide; siRNA delivery; Covalent CPP-siRNA chemical conjugate; Cell uptake mechanism; Cytotoxicity

Asghar Narmani, Mehdi Kamali, Bahram Amin, Ali Salimi, Yunes Panahi, Targeting delivery of oxaliplatin with smart PEG-modified PAMAM G4 to colorectal cell line: In vitro studies, Process Biochemistry, 2018, Keywords: MAL-PEG-NHS; Oxaliplatin delivery; PEG-PAMAM-FA-OX nano-complex; Colorectal cancer; Drug delivery

Katherine J.R. Lewis, Jessica K. Hall, Emi A. Kiyotake, Tova Christensen, Vivek Balasubramaniam, Kristi S. Anseth, Epithelial-mesenchymal crosstalk influences cellular behavior in a 3D alveolus-fibroblast model system, Biomaterials, Volume 155, 2018, Pages 124-134, Keywords: PEG4SH; Alveolar epithelium; Fibroblast; Co-culture; Hydrogel; Cancer; Matrix metalloproteinases

Hanmei Li, Yuna Tong, Lan Bai, Lei Ye, Lei Zhong, Xingmei Duan, Yuxuan Zhu, Lactoferrin functionalized PEG-PLGA nanoparticles of shikonin for brain targeting therapy of glioma, International Journal of Biological Macromolecules, Volume 107, Part A, 2018, Pages 204-211, Keywords: mPEG-NH2 and Mal-PEG-NH2, Shikonin; Glioma; Nanoparticles

Apurva Badkas, Evan Frank, Zilan Zhou, Mina Jafari, Harish Chandra, Vishnu Sriram, Joo-Youp Lee, Jagjit S. Yadav, Modulation of in vitro phagocytic uptake and immunogenicity potential of modified Herceptin®-conjugated PLGA-PEG nanoparticles for drug delivery, Colloids and Surfaces B: Biointerfaces, Volume 162, 2018, Pages 271-278, Keywords: NHS-PEG-methoxy and NHS-PEG-alkyne; Nanoparticle conjugate; Immunogenicity; Cellular uptake; Herceptin®; PLGA-PEG

Haojun Ma, Chen Jiang, Dehydroascorbic Acid and pGPMA Dual Modified pH-Sensitive Polymeric Micelles for Target Treatment of Liver Cancer, Journal of Pharmaceutical Sciences, Volume 107, Issue 2, 2018, Pages 595-603, Keywords: N3-PEG-NH2; drug delivery systems; polymeric drug delivery systems; cancer chemotherapy; biodegradable polymers; biomaterials; controlled release

Xu Wang, Changying Shi, Lili Wang, Juntao Luo, Polycation-telodendrimer nanocomplexes for intracellular protein delivery, Colloids and Surfaces B: Biointerfaces, Volume 162, 2018, Pages 405-414, Keywords: MeO-PEG-NH2HCl; Polycation; Telodendrimer; Nanocomplex; Intracellular protein delivery

Jinrui Shen, Heling Li, Cuifen Lu, Guichun Yang, Feiyi Wang, Junqi Nie, Xingjian Hu, Nianguo Dong, Jiawei Shi, Hydrolytically degradable POSS-PEG hybrid hydrogels prepared in aqueous phase with tunable mechanical properties, swelling ratio and degradation rate, Reactive and Functional Polymers, Volume 123, 2018, Pages 91-96, Keywords: 4arm-PEG-MAL; PEG; POSS; Hydrogels; Hydrolytically degradable; Michael-type addition

Chunhui Ruan, Lisha Liu, Yifei Lu, Yu Zhang, Xi He, Xinli Chen, Yujie Zhang, Qinjun Chen, Qin Guo, Tao Sun, Chen Jiang, Substance P-modified human serum albumin nanoparticles loaded with paclitaxel for targeted therapy of glioma, Acta Pharmaceutica Sinica B, Volume 8, Issue 1, 2018, Pages 85-96, Keywords: MAL-PEG-NHS; Human serum albumin; Paclitaxel; Drug delivery; Substance P; Blood–brain barrier; Glioma

Shweta Sharma, Aman P. Mann, Tarmo Mölder, Venkata Ramana Kotamraju, Robert Mattrey, Tambet Teesalu, Erkki Ruoslahti, Vascular changes in tumors resistant to a vascular disrupting nanoparticle treatment, Journal of Controlled Release, Volume 268, 2017, Pages 49-56. Keywords: MAL-PEG-NHS;Tumor angiogenesis; Tumor homing peptide; Phage display; Drug resistance; Integrins

Zhi-qiang Yuan, Wei-liang Chen, Ben-gang You, Yang Liu, Shu-di Yang, Ji-zhao Li, Wen-jing Zhu, Xiao-feng Zhou, Chun Liu, Xue-nong Zhang, Multifunctional nanoparticles co-delivering EZH2 siRNA and etoposide for synergistic therapy of orthotopic non-small-cell lung tumor, Journal of Controlled Release, Volume 268, 2017, Pages 198-211. Keywords: M-PEG-SCM and MAL-PEG-SCM; NSCLC; EZH2 siRNA; ETP; NPs; Co-delivery system

Karla Alejo-González, Katrin Quester, Erik Hanson, Ismael Secundino, Yvonne Rosenstein, Alejandro Huerta-Saquero, Rafael Vazquez-Duhalt, PEGylation of cytochrome P450 enhances its biocatalytic performance for pesticide transformation, International Journal of Biological Macromolecules, Volume 105, Part 1, 2017, Pages 163-170. Keywords: M-PEG-NHS ; Cytochrome P450; CYP; Pesticide transformation; Polyethylene glycol; PEG

W. Hampton Henley, Yan He, J. Scott Mellors, Nicholas G. Batz, J. Michael Ramsey, James W. Jorgenson, High resolution separations of charge variants and disulfide isomers of monoclonal antibodies and antibody drug conjugates using ultra-high voltage capillary electrophoresis with high electric field strength, Journal of Chromatography A, Volume 1523, 2017, Pages 72-79, ISSN 0021-9673. Keywords: Methoxy PEG Succinimidyl Carboxymethyl Ester; Ultra-high voltage capillary electrophoresis; High electric field strength; High performance separation; Disulfide isomer; Monoclonal antibody; Antibody drug conjugate

Asghar Narmani, Kamal Yavari, Javad Mohammadnejad, Imaging, biodistribution and in vitro study of smart 99mTc-PAMAM G4 dendrimer as novel nano-complex, Colloids and Surfaces B: Biointerfaces, Volume 159, 2017, Pages 232-240. Keywords: MAL-PEG-NHS; Breast cancer targeting; Folic acid and 5-FU; 99mTc; Cellular uptake and viability; Biodistribution; Imaging

Christina L. Parker, Qi Yang, Bing Yang, Justin D. McCallen, Steven I. Park, Samuel K. Lai, Multivalent interactions between streptavidin-based pretargeting fusion proteins and cell receptors impede efficient internalization of biotinylated nanoparticles, Acta Biomaterialia, Volume 63, 2017, Pages 181-189. Keywords: Methoxy PEG Amine and Biotin PEG Amine; Intracellular delivery; Pretargeting; Bispecific

Mona Alibolandi, Rouhollah Rezvani, Sara Amel Farzad, Seyed Mohammad Taghdisi, Khalil Abnous, Mohammad Ramezani, Tetrac-conjugated polymersomes for integrin-targeted delivery of camptothecin to colon adenocarcinoma in vitro and in vivo, International Journal of Pharmaceutics, Volume 532, Issue 1, 2017, Pages 581-594. Keywords: NH2-PEG-CM; Tetrac; Camptothecin; Polymersomes; Colon adenocarcinoma; PEG-PLGA

Kruti S. Soni, Fan Lei, Swapnil S. Desale, Luis A. Marky, Samuel M. Cohen, Tatiana K. Bronich, Tuning polypeptide-based micellar carrier for efficient combination therapy of ErbB2-positive breast cancer, Journal of Controlled Release, Volume 264, 2017, Pages 276-287. Keywords: mPEG-NH2 and Fmoc-PEG-NH2

Zhilan Chai, Xuefeng Hu, Xiaoli Wei, Changyou Zhan, Linwei Lu, Kuan Jiang, Bingxia Su, Huitong Ruan, Danni Ran, Ronnie H. Fang, Liangfang Zhang, Weiyue Lu, A facile approach to functionalizing cell membrane-coated nanoparticles with neurotoxin-derived peptide for brain-targeted drug delivery, Journal of Controlled Release, Volume 264, 2017, Pages 102-111. Keywords: MAL-PEG-NH2; Biomimetic nanoparticles; Brain-targeting; BBB; DCDX; Glioma

Haojun Ma, DHA and pGPMA Dual Modified pH Sensitive Polymeric Micelles for Target Treatment of Liver Cancer, Journal of Pharmaceutical Sciences, 2017; Keywords: Azide PEG Amine.

Tugba Ozdemir, Padma Pradeepa Srinivasan, Daniel R. Zakheim, Daniel A. Harrington, Robert L. Witt, Mary C. Farach-Carson, Xinqiao Jia, Swati Pradhan-Bhatt, Bottom-up assembly of salivary gland microtissues for assessing myoepithelial cell function, Biomaterials, 2017, Volume 142,  Pages 124-135. Keywords: PEG Bismaleimide; Salivary glands; Myoepithelial cells; Stem/progenitor cells; Spheroids; Self-assembly; Microtissues

Yanna Yu, Zhipeng Zhang, Yun Wang, Hao Zhu, Fangzhou Li, Yuanyuan Shen, Shengrong Guo, A new NIR-triggered doxorubicin and photosensitizer indocyanine green co-delivery system for enhanced multidrug resistant cancer treatment through simultaneous chemo/photothermal/photodynamic therapy, Acta Biomaterialia, Volume 59, 2017, Pages 170-180. Keywords: Biotin-PEG-NHS and mPEG-NHS; NIR-triggered; Gold nanocages; Photodynamic therapy; Photothermal therapy; Multidrug resistant

Sytze J. Buwalda, Pieter J. Dijkstra, Jan Feijen, In situ forming stereocomplexed and post-photocrosslinked acrylated star poly(ethylene glycol)-poly(lactide) hydrogels, European Polymer Journal, Volume 94, 2017, Pages 152-161. Keywords: 8arm PEG Raw Material, PEG-(OH)8; Tandem gelation; Stereocomplexation; Photocrosslinking; PEG-PLA; Star block copolymer

Joelle Bizeau, Christos Tapeinos, Claudio Marella, Aitor Larrañaga, Abhay Pandit, Synthesis and characterization of hyaluronic acid coated manganese dioxide microparticles that act as ROS scavengers, Colloids and Surfaces B: Biointerfaces, Volume 159, 2017, Pages 30-38, Keywords: 4-arm PEG-amine; Atherosclerosis; Drug delivery; Manganese dioxide; Microspheres; ROS scavenging

Kyuri Lee, Allan E. David, Jian Zhang, Meong Cheol Shin, Victor C. Yang, Enhanced accumulation of theranostic nanoparticles in brain tumor by external magnetic field mediated clustering of magnetic nanoparticles, Journal of Industrial and Engineering Chemistry, Volume 54, 2017, Pages 389-397, Keywords: NHS-PEG-SH; Magnetic iron oxide nanoparticles (MIONs); Magnetically guided drug delivery; Brain tumor; in situ formation

Dan Liu, Xingrui Li, Junkai Zhou, Shibo Liu, Tian Tian, Yanling Song, Zhi Zhu, Leiji Zhou, Tianhai Ji, Chaoyong Yang, A fully integrated distance readout ELISA-Chip for point-of-care testing with sample-in-answer-out capability, Biosensors and Bioelectronics, Volume 96, 2017, Pages 332-338, Keywords: mPEG-SH; ELISA; Distance readout; Microfluidics; Point-of-care testing

Shanshan Wang, Chengyi Li, Min Qian, Huiling Jiang, Wei Shi, Jian Chen, Ulrich Lächelt, Ernst Wagner, Weiyue Lu, Yi Wang, Rongqin Huang, Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots, Biomaterials, Volume 141, 2017, Pages 29-39, Keywords: NHS-PEG-MAL; Polymer-coated carbon nanodots; Blood-brain barrier; Interleukin-6 receptor; Real-time monitoring; Theranostics

Sadhana Sharma, Michael Floren, Yonghui Ding, Kurt R. Stenmark, Wei Tan, Stephanie J. Bryant, A photoclickable peptide microarray platform for facile and rapid screening of 3-D tissue microenvironments, Biomaterials, Volume 143, 2017, Pages 17-28, Keywords: 4-arm PEG amine; Fibrous hydrogel; Photoclickable; Peptide microarray; High-throughput screening; Cell-matrix interaction; Cell-cell interaction; Tissue microenvironments

Kyle A. DiVito, Michael A. Daniele, Steven A. Roberts, Frances S. Ligler, André A. Adams, Data characterizing microfabricated human blood vessels created via hydrodynamic focusing, Data in Brief, Volume 14, 2017, Pages 156-162, Keywords: tetrathiol- and acrylate-modified poly(ethylene) glycol; Microfluidics; GelMA; Endothelial cell; Blood vessel; Microvessel; Organ-on-chip

Dandan Guo, Changying Shi, Xu Wang, Lili Wang, Shengle Zhang, Juntao Luo, Riboflavin-containing telodendrimer nanocarriers for efficient doxorubicin delivery: High loading capacity, increased stability, and improved anticancer efficacy, Biomaterials, Volume 141, 2017, Pages 161-175, Keywords: Methoxy PEG Amine; Rational nanocarrier design; Telodendrimer; High loading capacity; Controlled drug release; Targeted therapy; Cancer treatment

Panagiotis Mastorakos, Clark Zhang, Eric Song, Young Eun Kim, Hee Won Park, Sneha Berry, Won Kyu Choi, Justin Hanes, Jung Soo Suk, Biodegradable brain-penetrating DNA nanocomplexes and their use to treat malignant brain tumors, Journal of Controlled Release, Volume 262, 2017, Pages 37-46, Keywords: Methoxy-PEG-succinimidyl succinate; Biodegradable polymer; DNA nanocomplex; Non-viral gene therapy; Tumor tissue barrier; Convection enhanced delivery

Hui Li, Ping Wang, Yunxiang Deng, Meiying Zeng, Yan Tang, Wei-Hong Zhu, Yingsheng Cheng, Combination of active targeting, enzyme-triggered release and fluorescent dye into gold nanoclusters for endomicroscopy-guided photothermal/photodynamic therapy to pancreatic ductal adenocarcinoma, Biomaterials, Volume 139, 2017, Pages 30-38, Keywords: Thiol PEG Succinimidyl Propionate; Gold nanoclusters; Fluorescent bioimaging; Pancreatic ductal adenocarcinoma; Enzyme-triggered release; Photothermal and photodynamic therapy

Kyle A. DiVito, Michael A. Daniele, Steven A. Roberts, Frances S. Ligler, André A. Adams, Microfabricated blood vessels undergo neoangiogenesis, Biomaterials, Volume 138, 2017, Pages 142-152, Keywords: PEG tetrathiol and PEG acrylate; Sheath-flow microfluidics; Blood vessel; Angiogenesis; Anastomoses; Perfusion

Yu Li, Ying Chen, Dongmei Deng, Liqiang Luo, Haibo He, Zhenxin Wang, Water-dispersible graphene/amphiphilic pyrene derivative nanocomposite: High AuNPs loading capacity for CEA electrochemical immunosensing, Sensors and Actuators B: Chemical, Volume 248, 2017, Pages 966-972. Keywords: 4arm-PEG-NH2; Graphene; Amphiphilic pyrene derivative; 4-armed poly(ethylene glycol)-NH2; Gold nanoparticles; Impedimetric immunosensor

Chun Zhang, Rong Yu, Zenglan Li, Cui Feng, Qi Wang, Yongdong Liu, Zhiguo Su, Development of long-acting ciliary neurotrophic factor by site-specific conjugation with different-sized polyethylene glycols and transferrin, International Journal of Pharmaceutics, Volume 529, Issue 1, 2017. Keywords: Methoxy PEG Maleimide; PEGylation; Transferrin coupling; Long-acting; Ciliary neurotrophic factor; Anti-obese

Hedi Hunt, Lorena Simón-Gracia, Allan Tobi, Venkata Ramana Kotamraju, Shweta Sharma, Mait Nigul, Kazuki N. Sugahara, Erkki Ruoslahti, Tambet Teesalu, Targeting of p32 in peritoneal carcinomatosis with intraperitoneal linTT1 peptide-guided pro-apoptotic nanoparticles, Journal of Controlled Release, Volume 260, 2017, Pages 142-153. Keywords: Maleimide PEG Succinimidyl Carboxymethyl Ester; Peptide; p32; Neuropilin-1; Nanomedicine; Iron oxide nanoworms; Pro-apoptotic peptide; Tumor targeting; Peritoneal carcinomatosis; MR imaging

Steven K. Jones, Anwesha Sarkar, Daniel P. Feldmann, Peter Hoffmann, Olivia M. Merkel, Revisiting the value of competition assays in folate receptor-mediated drug delivery, Biomaterials, Volume 138, September 2017, Pages 35-45; Keywords: Methoxy PEG Acetic Acid; Folate receptor targeting; siRNA delivery; Polymer micelleplexes; Atomic force microscopy; Competitive uptake; Receptor ligand interaction;

Xiaodan Li, Min Gao, Keting Xin, Ling Zhang, Dan Ding, Deling Kong, Zheng Wang, Yang Shi, Fabian Kiessling, Twan Lammers, Jianjun Cheng, Yanjun Zhao, Singlet oxygen-responsive micelles for enhanced photodynamic therapy, Journal of Controlled Release, Volume 260, 28 August 2017, Pages 12-21; Keywords: Methoxy PEG Amine; Micelles; Photodynamic therapy; Singlet oxygen-responsive; Imidazole; Drug delivery

Lisa Racine, Guillaume Costa, Eric Bayma-Pecit, Isabelle Texier, Rachel Auzély-Velty, Design of interpenetrating chitosan and poly(ethylene glycol) sponges for potential drug delivery applications, Carbohydrate Polymers, Volume 170, 15 August 2017, Pages 166-175; Keywords: 4arm PEG Amine; Chitosan; Poly(ethylene) glycol; Sponges; Semi-interpenetrating network

Xiaofeng Han, Xuerong Dong, Jing Li, Manyuan Wang, Lei Luo, Zhaoxia Li, Xuran Lu, Rui He, Rongsong Xu, Muxin Gong, Free paclitaxel-loaded E-selectin binding peptide modified micelle self-assembled from hyaluronic acid-paclitaxel conjugate inhibit breast cancer metastasis in a murine model, International Journal of Pharmaceutics, Volume 528, Issues 1–2, 7 August 2017, Pages 33-46. Keywords: Maleimide PEG Succinimidyl Carboxymethyl Ester; Breast cancer metastasis; Hyaluronic acid; Paclitaxel; E-selectin; E-selectin binding peptide; Drug delivery system

Rebecca A. Scott, Prathamesh M. Kharkar, Kristi L. Kiick, Robert E. Akins, Aortic adventitial fibroblast sensitivity to mitogen activated protein kinase inhibitors depends on substrate stiffness, Biomaterials, Volume 137, August 2017, Pages 1-10. Keywords: 4arm PEG Thiol; Hydrogel; Fibroblast; Mitogen-activated protein kinase; Cytokine; Vascular graft

Manfred F. Maitz, Jan Zitzmann, Jasmin Hanke, Claudia Renneberg, Mikhail V. Tsurkan, Claudia Sperling, Uwe Freudenberg, Carsten Werner, Adaptive release of heparin from anticoagulant hydrogels triggered by different blood coagulation factors, Biomaterials, Volume 135, August 2017, Pages 53-61, Keywords: 4arm PEG Maleimide; Hydrogel; Bioresponsive; Anticoagulation; Thrombin; Factor Xa

Shuangli Xiao, Zhongbing Liu, Ruolan Deng, Chunhong Li, Shaozhi Fu, Guilan Chen, Xiaoqin Zhang, Famin Ke, Siyun Ke, Xin Yu, Shurong Wang, Zhirong Zhong, Aptamer-mediated gene therapy enhanced antitumor activity against human hepatocellular carcinoma in vitro and in vivo, Journal of Controlled Release, Volume 258, 28 July 2017, Pages 130-145, Keywords: PEG (Acetic Acid)2; Recombinant adenovirus; PTEN; Aptamer EpDT3; Gene delivery system; Antitumor activity; Human hepatocellular carcinoma